Irb 101.

IRB Process Improvements: A Machine Learning Analysis

OBJECTIVE Clinical research involving humans is critically important, but it is a lengthy and expensive process. Most studies require institutional review board (IRB) approval. Our objective is to identify predictors of delays or accelerations in the IRB review process and apply this knowledge to inform process change in an effort to improve IRB efficiency, transparency, consistency and communi...

Retrospective chart review of catatonia in child and adolescent psychiatric patients.

OBJECTIVE Identify the frequency of catatonia among at-risk children and adolescents receiving psychiatric treatment. METHOD Subjects were children and adolescents (<18 years), who had received psychiatric treatment at a University Hospital during 2004-2009, and were diagnosed with disorders with known risk for catatonia or displayed symptoms suggestive of catatonia. Approval was obtained fro...

Biobanking Research and Human Subjects Protections: Perspectives of IRB Leaders.

IRB Accreditation and Local IRB Operations

Understanding institutional review boards: practical guidance to the IRB review process.

The purpose of this paper is to provide practical guidance to assist investigators in the preparation of materials and obtaining approval for research projects that require oversight by an institutional review board (IRB). The central requirements for IRB approval and core considerations of IRBs are described. Specific suggestions for investigators regarding how to prepare their IRB application...